Protein C derivatives

Details Protein C derivatives Protein C derivatives

2006-02-14

2006-02-14

Prouty, Rebecca (Department: 1652)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C435S226000, C435S320100, C435S325000, C536S023200

Reexamination Certificate

active

06998122

ABSTRACT:
Novel protein C derivatives are described. These polypeptides retain the biological activity of the wild-type human protein C with substantially longer half-lives in human blood. These polypeptides will require either less frequent administration and/or smaller dosage than wild-type human protein C in the treatment of vascular occlusive disorders, hypercoagulable states, thrombotic disorders and disease states predisposing to thrombosis.

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