Protein biosensor and method for protein measurement with the sa

Electrolysis: processes – compositions used therein – and methods – Electrolytic analysis or testing – Using ion exchange resin

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204403, G01N 2726

Patent

active

056538642

ABSTRACT:
A protein biosensor, which comprises an insulating substrate, a working electrode, a counter-electrode and a reference electrode, each electrodes provided on the insulating substrate, the working electrode comprising a first lead electrode and a thin protein-sensitive metallic film provided on the first lead electrode and the reference electrode comprising a second lead electrode and a silver/silver chloride electrode provided on the second lead electrode is simple in the structure and can be made smaller in the size, enabling easy manufacturing and operation, where measurement of a protein concentration is carried out with a carrier containing KCl or NaCl as dissolved therein.

REFERENCES:
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patent: 4871440 (1989-10-01), Nagata et al.
Hitchman et al.; J. Chem. Soc., Faraday Trans. 1; "Potentiometric Monitoring of Proteins"; 1986, 82, 1223-1236 1986 No month available.
Hitchman et al.; Analytica Chimica Acta; "Direct Potentiometric Monitoring of Proteins", 155 (1983) 219-224 1983 No month available.
Yuan et al.; Anal. Chem.; "Determination of Proteins and Denaturation Studies by Flow Injection with a Nickel Oxide Electrode", 1985, 57, 180-185 1985 No month available.
Kelly et al.; J. Chem. Soc., Faraday Trans. 1., "Solid-State Ion Sensors:Theoretical and Practical Issues", 1986, 82, 1195-1208 1986 No month available.
Alexander et al.; Analytica Chimica Acta; "Potentiometric Flow-Injection Determination of Copper-Complexing Organic Ligands with a Copper-Wire Indicating Electrode", 171(1985) 151-163 No month available 1985.
Hui et al.; Analytica Chimica Acta; "Temperature Effects on Amperometric Detection at Nickel Oxide Electrodes in Flow-Injection Systems", 197(1987) 361-365 No month available 1987.

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