Protein and DNA thereof

Details Protein and DNA thereof Protein and DNA thereof

2005-01-18

2005-01-18

Rao, Manjunath (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S004000, C435S006120, C435S069100, C435S183000, C435S200000, C435S252300, C435S320100, C536S023200, C536S023500

Reexamination Certificate

active

06844179

ABSTRACT:
The protein of the present invention and a DNA encoding the same can be used as therapeutic/prophylactic agents for diseases such as infectious diseases. The protein of the present invention is also useful as a reagent for screening a compound or its salt capable of promoting or inhibiting the activity of the protein of the present invention. Furthermore, a compound or its salt inhibiting the activity of the protein of the present invention and a neutralization antibody inhibiting the activity of the protein of the present invention can also be used as therapeutic/prophylactic agents for diseases such as bronchial asthma, chronic obstructive pulmonary disease, etc.

REFERENCES:
Chang et al. (Genbank Accession No. S27879, Apr. 17, 1993).*
Saito et al (GenBank accession No. Q9ULY4, May 1, 2000.*
A Saito, et al. “Isolation and mapping of a human lung-specific gene, TSA 1902, encoding a novel chitinase family member” GENE 239: 325-31-No 2(1999).
M. Owhash. “Identification of a Novel Eosinophil Chemotactic Cytokine (ECF-L) as a Chitinase Family Protein” Journal of Biological Chemistry 275: 1279-86, No. 2 (2000).

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