Protein AMSH and cDNA thereof

Details Protein AMSH and cDNA thereof Protein AMSH and cDNA thereof

1999-11-12

2008-09-09

Saoud, Christine J. (Department: 1646)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023500, C435S235100, C435S325000, C435S320100, C435S069100, C053S350000

Reexamination Certificate

active

07423134

ABSTRACT:
This application provides a human protein AMSH having the amino acid sequence of SEQ ID No. 1 which is a novel signal transduction molecule interacting with the SH3 domain of cytokine based signal transduction molecule STAM; a gene encoding the above AMSH; a cDNA having the nucleotide sequence of SEQ ID No. 2; and antibody against AMSH.

REFERENCES:
patent: 6468546 (2002-10-01), Mitcham et al.
patent: 2003/0073623 (2003-04-01), Drmanac et al.
patent: WO 01/21794 (2001-03-01), None
Andersson et al. (1996), A “Double Adaptor” Method for Improved Shotgun Library Construction, Analytical Biochemistry, 236: 107-113.
Yu et al. (1997), Large-Scale Concatenation cDNA Sequencing, Genome Res. 7(4): 353-358.
Alignment of SEQ ID No. 2 and NCBI Accession No. AF052135.
Yu et al., NCBI Accession No. AF052135, Aug. 5, 1998,Homo sapiensclone 23625 mRNA sequence.
Hutchinson et al (Nucleic Acids Research, 1992, vol. 20, No. 13, pp. 3458-3462).
Solovyev et al (Nucleic Acids Research, 1994, vol. 22, No. 24, pp. 5156-5163).
Eberhard Passarge (Color Atlas of Genetics, Georg Thieme Verlag Stuttgart, New York, Thieme Medical publishers, Inc. New York, pp. 48-49, 1995).
GenEmbl database, ACCESSION No. AF052135, Aug. 5, 1998.
GenEmbl database, ACCESSION No. U73522, Jun. 29, 1999.
Tanaka et al (J. Biol. Chem. 274 (27), 19129-19135, Jul. 2, 1999, article provided as pp. 1/1-1/9.
Kazuo Sugamura et al., “Possible involvement of a novel STAM-associated molecule “AMSH” in intracellular signal transduction mediated by cytokines”, J. Biol. Chem., vol. 274, No. 27, pp. 19129-19135, Jul. 1999.
Wei Yu et al., “Large-scale concatenation cDNA sequencing”, Genome Research, vol. 7, No. 4, pp. 353-358, 1997.
Meredith A. Wentland et al., “A “double adaptor” method for improved shotgun library construction”, Analytical Biochemistry, vol. 236, No. 1, pp. 107-113, 1996.
K. Sugamura et al., “STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction”, Immunity, vol. 6, No. 4, pp. 449-457, 1997.

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