Protein allergen of Derf II and composition

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

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4241931, 4242751, 530350, 530395, A61K 3900, A61K 39385, A61K 3935, C07K 100

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active

059584157

ABSTRACT:
The invention provides at least one protein which has biochemical and immunological properties of a major allergen of Dermatophagoides farinae (Derf II).

REFERENCES:
patent: 4837148 (1989-06-01), Cregg
patent: 4879213 (1989-11-01), Fox et al.
patent: 5433948 (1995-07-01), Thomas et al.
patent: 5552142 (1996-09-01), Thomas et al.
patent: 5798099 (1998-08-01), Yuuki et al.
Bowie et al, "Deciphering the message in protein sequences: Tolerance to amino acid substitutions", Science 247:1306-1310 (1990).
Chua et al, "Sequence analysis of cDNA coding for a major house dust mite allergen, Derp I", J. Exp. Med. 167:175-182 (Jan. 1988).
Chua et al, "Isolation of cDNA coding for the major mite allergen Der p II by IgE plaque immuno-assay", Int. Arch. Allergy Appl. Immunol. 91:118-123 (1990).
Chua et al, "Expression of Dermatophagoides pteronyssinus allergen, Der p II, in Escherichia coli and the binding studies with human IgE", Int. Arch. Allergy Appl. Immunol. 91:124-129 (1990).
Ford et al, "Standardization of Dermatophagoides pteronyssinus: Assessment of potency and allergen content in ten coded extracts", Int. Archs Allergy Appl. Immun. 76:58-67 (1985).
Greene et al, "Antigenic analysis of group I house dust mite allergens using random fragments of Der p I expressed by recombinant DNA libraries", Int Arch Allergy Appl Immunol 92:30-38 (1990).
Haida et al, "Allergens of the house dust mite Dermatophagoides farinae--Immunochemical studies of four allerlgenic fractions", J. Allergy Clin. Immunol. 75(6):686-692 (Jun. 1985).
Heymann et al, "Antigen Der f I from the dust mite Dermatophagoides farinae: Structural comparison with Der p I from Dermatophagoides pteronyssinus and epitope specificity of murine IgG and human IgE antibodies", The Journal of Immunology 137:2841-2847 (1986).
Ino et al, "Characterization of the proteases in the crude mite extract", Int Arch Allergy Appl Immunol 89:321-326 (1989).
Kumar et al, "Amino acid variations at a single residue in an autoimmune peptide profoundly affect its properties: T-cell activation, major histocompatibility complex binding, and ability to block experimental allergic encaphalomyelitis", Proc. Natl. Acad. Sci. USA 87:1337-1341 (1990).
Maniatis et al, Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, 1982, pp. 226-228, 411-413 and 422 (1982).
Stewart et al, "In vitro translation of messenger RNA from the house dust mite Dermatophagoides pteronyssinus", Int. Archs Allergy Appl. Immun. 83:384-389 (1987).
Suggs et al, "Use of synthetic oligonucleotides as hybridization probes: Isolation of cloned cDNA sequences for human beta2-microglobulin", Proc. Natl. Acad. Sci. USA 78(11):6613-6617 (1981).
Thomas et al, "Cloning and expression of DNA coding for the major house dust mite allergen Der p 1 in Escherichia coli", Int. Archs Allergy Appl. Immun. 85:127-129 (1988).
Thomas et al, "Analysis and expression of cDNA clones coding for house dust mite allergens", Advances in Biosciences 74:139-147 (1989).
Tovey et al, "Cloning and sequencing of a cDNA expressing a recombinant house dust mite protein that binds human IgE and corresponds to an important low molecular weight allergen", J. Exp. Med. 170:1457-1462 (1989).
Yamashita et al, "Allergens of the house dust mite Dermatophagoides farinae. II. Immunological characterization of four allergenic molecules", Int Arch Allergy Appl Immunol 88:173-375 (1988).
Yasueda et al, "Isolation and characterization of two allergens from Dermatophagoides farinae", Int. Archs Allergy Appl. Immun. 81:214-223 (1986).
Yasueda et al, "Comparative analysis of physicochemical and immunochemical properties of the two major allergens from Dermatophagoides pteronyssinus and the corresponding allergens from Dermatophagoides farinae", Int Arch Allergy Appl Immunol 88:402-407 (1989).
Yasueda et al, "Measurement of allergens associated with dust mite allergy", Int Arch Allergy Appl Immunol 90:182-189 (1989).
Young et al, "Efficient isolation of genes by using antibody probes", Proc. Natl. Acad. Sci. USA 80:1194-1198 (1983).
Yuuki et al, "Cloning and sequencing of cDNAS corresponding to mite major allergen Der f II", Jpn. J. Allergol. 39:557-561 (1990).
Chapman et al, Epitope mapping of major dust mite (dermatophagoides) allergens using monoclonal antibodies. In: Mite Allergy (Eds. A.L. de Weck, A. Todt), The UCB Institute of Allergy, Brussels, pp. 27-29, 1987.

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