Protein adsorbent and process for the purification of urokinase

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 18, 536 30, 536 51, C08B 3700, C08B 3702, C08B 1506

Patent

active

043072283

ABSTRACT:
A novel protein adsorbent having a group of the general formula ##STR1## wherein X is hydrogen, halogen, amino, lower alkyl or lower alkoxycarbonyl as a ligand, is useful for the purification of urokinase by hydrophobic chromatography, particularly for the removal of the kinds of pyrogen that can only be removed with great difficulty by affinity chromatography on the ordinal adsorbent of urokinase.

REFERENCES:
patent: 2798079 (1957-07-01), Linn
patent: 3947352 (1976-03-01), Cuatrecasas et al.
patent: 4011205 (1977-03-01), Dean et al.
patent: 4020268 (1977-04-01), Nishikawa et al.

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