Protein

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing

Reexamination Certificate

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C514S002600, C435S007100, C536S023740, C424S094600

Reexamination Certificate

active

07371375

ABSTRACT:
A nucleic acid comprising a nucleotide sequence encoding a lysin, which nucleotide sequence comprises the sequence shown in SEQ ID No. 1 or a variant, homologue or derivative thereof. A novel lysin obtainable from a bacteriophage capable of colonisingClostridium perfringens, and the use thereof as a medicament for the treatment of a disorder associated with pathogenicClostridiumbacteria, for example.

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Ishikawa et al., “Cloning and expression of two autolysin genes, cwIU and cwIV, which are tandemly arranged on the chromosome ofBacillus polymyxavar. colistimus,”Mol. Gen. Genet., 262:738-748, 1999.
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