Protein

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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530350, 5303871, 536 231, 536 234, 514895, 935 47, 935 12, 435 691, 435 693, 435 697, 4241301, 4241561, 4241841, 4241851, 4241911, 4241921, 4242681, 4242691, A61K 39015, C07K 100, C07K 2102, C12N 1500, C07H 2102

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057981060

ABSTRACT:
This invention relates to a novel protein capable of inducing an immune response protective against human malarial infection caused by Plasmodium falciparum, and to the cloning and expression of a gene encoding the said protein. The invention further relates to novel vaccines comprising the said protein and to their use in the vaccination of humans at risk from malaria.

REFERENCES:
patent: 4879213 (1989-11-01), Fox et al.
Kaslow "Immunology Letters" (1990) vol. 25, 83-86.
Lazar et al. Mol. & Cell Biol. (1988) vol. 8(3), 1247-1252.
Burgess et al. The J. Cell. Biol. (1990) vol. III (Nov.) 2129-2138.
Lehringer in Biochemistry 2.sup.nd Edition, Worth Publishers Iwe., NY, NY (1975), p. 63.
Eisen in "Immunology" 2nd Edition, Harper & Ron Publishers, Hagerslown, PA (1980), p. 436.
Cox, "Tibtech" vol. 9 pp. 389-394 (1991).
Mitchell, "Parasitology" (1989) vol. 98, pp. 529-547.

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