Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Derived from transgenic multicellular eukaryote
Patent
1981-10-30
1983-07-05
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Derived from transgenic multicellular eukaryote
424141, 424143, 424290, 424364, 424DIG13, A61K 3338
Patent
active
043917992
ABSTRACT:
Water soluble hydrogels of alkali metal alginate and glycerin containing 0.01 to 1% cupric (copper) sulfate pentahydrate or silver salts such as silver acetate, silver lactate monohydrate and silver nitrate have been found to be excellent wound dressing treatment composition for white phosphorus burns.
Cupric sulfate pentahydrate or silver salts such as silver acetate, silver lactate monohydrate and silver nitrate in the gel reacts with the particles of white phosphorus to form a coating around said particles thus rendering them unable to cause further burn injury to the skin. The gels dry to an adherent, non-toxic pliable protective film which can be removed by water-washing when desired. The gels are also compatible with other medicaments and hence can serve as vehicles or carriers for medicament application to wounds as well as a protective cover.
REFERENCES:
patent: 2338416 (1944-01-01), Fales
patent: 2405861 (1946-08-01), Tod
patent: 2845381 (1958-07-01), Tindall
patent: 3639575 (1972-02-01), Schmolka
Gooding et al., Journal of the American Medical Assoc., (1942), p. 1059.
Stadlinger; Chemical Abstracts, vol. 39, p. 2587, "Treatment of Phosphorus urns".
Lachman et al., The Theory & Practice of Industrial Pharmacy, 2nd ed., (1976), pp. 229-230.
Johnson, Jr. Avery A.
Mason, Jr. Arthur D.
Ritchey Charles R.
Bellamy Werten F. W.
Gapcynski William G.
Petruncio Jack M.
Schenkman Leonard
The United States of America as represented by the Secretary of
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