Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1994-09-28
1997-07-22
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
4242451, 4242661, 530350, 530412, A61K 39002, A61K 3905
Patent
active
056501544
ABSTRACT:
Methods and kits for identifying antigens from a pathogen. The antigens identified are preferably those that provide protection for an animal against the pathogen. The steps of the method include providing a sample of the pathogen, isolating the protective antigen from the sample of antigen with an antibody probe. The antibody probe is produced by obtaining a biological sample containing antibody producing cells from an immune animal infected with or challenged by the pathogen or pathogen extract, and obtaining the antibodies from these cells by culturing the cells. These methods and kits are useful for preparing antigens to be used as vaccines, in diagnostic kits, and to prepare polyclonal or monoclonal antibodies.
REFERENCES:
patent: 3853990 (1974-12-01), Madigan et al.
patent: 4743446 (1988-05-01), Bennett
Roitt, et al., Immunology, Gower Medical Publishing, pp. 8.1-8.2 and p. 25.7 (1985).
Bowles Vernon Morrison
Brandon Malcolm Roy
Gorrell Mark Douglas
Theresia Meeusen Elza Nicole
Walker John
Housel James C.
Swartz Rodney P.
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