Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2011-02-22
2011-02-22
Duffy, Patricia A (Department: 1645)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387500, C530S387300, C435S341000, C424S133100, C424S135100, C424S137100
Reexamination Certificate
active
07893219
ABSTRACT:
Anti-β-1,3-glucan antibodies have been found to be protective against systemic fungal infection withCandida albicans. The present invention provides monoclonal antibodies that bind to β-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly againstCandida albicansandAspergillus fumigatisinfections. The antibodies of the present invention are not specific for β-1,6-glucan.
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Cassone Antonio
Torosantucci Antonella
Duffy Patricia A
Novartis Vaccines & Diagnostics, Inc.
Robins & Pasternak LLP
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