Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1988-06-15
1993-02-02
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 88, 4351721, 4352534, 435885, A61K 3902, C12N 1500
Patent
active
051836599
ABSTRACT:
A new bacterial vaccine to protect susceptible equine against S. equi which causes strangles. The vaccine stimulates a nasopharyngeal immune response in a susceptible equine through the presence of antibody activity in the nasopharyngeal mucus. The vaccine is a S. equi strain which contains an M protein fragment of 41,000 mw and is adapted for administration to equine either intranasally or orally as a vaccine. There is described a new strain of S. equi (709-27), a method of making and isolating useful vaccine strain of S. equi bacteria which stimulates an antibody response in the nasopharyngeal mucosa of the susceptible equine.
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Timoney et al., Infection and Immunity, vol. 48, No. 1, pp. 29-34, Apr. 1985.
Barnard Ralph R.
Brown Johnnie R.
Cornell Research Foundation Inc.
Mohamed Abdel A.
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