Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Treating animal or plant material or micro-organism
Patent
1993-10-15
1997-02-04
Stone, Jacqueline M.
Chemistry: molecular biology and microbiology
Process of utilizing an enzyme or micro-organism to destroy...
Treating animal or plant material or micro-organism
4353201, 514 44, 424 9321, 424 932, A61K 4800, C12N 1500
Patent
active
055997120
ABSTRACT:
A method of protecting a subject against an agent that elicits production of toxic free radicals, superoxide anions, or heavy metal cations in the subject consisting of the in vivo administration to the subject of a polynucleotide encoding a protein that is transiently expressed in said subject. The transiently expressed protein is capable of neutralizing or eliminating the toxic free radicals, superoxide anions or heavy metal cations that are elicited by the agent. This method is particularly useful in protecting cancer patients against the damaging effects of ionizing radiation and chemotherapeutic drugs.
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Milne Andrew
Stone Jacqueline M.
University of Pittsburgh
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