Protection against chemically-induced kidney damage by methimazo

Details Protection against chemically-induced kidney damage by methimazo Protection against chemically-induced kidney damage by methimazo

1989-12-22

1991-04-23

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514360, 514365, 514385, 514395, 514869, 514922, 514219, 424 10, A01N 4364, A01N 4382, A01N 4378, A01N 4350

Patent

active

050100920

ABSTRACT:
Drug treatment therapies and kits for use therewith are disclosed. They involve the use of methimazole and/or its pro-drug carbimazole to reduce nephrotoxic effects of chemical exposure. In one embodiment, a patient receives cisplatin and then is treated with methimazole. The time delay in providing methimazole prevents the methimazole from being substantially expelled by the kidney prior to cisplatin reaching the kidney.

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