Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1998-06-24
1999-09-28
Kunz, Gary L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 221, 536 245, 536 2534, C07H 1904
Patent
active
059590998
ABSTRACT:
A 2-N-amidoethyl protected nucleoside analog phosphoramidite of formula (1): ##STR1## is useful in the synthesis of a wide variety of oligonucleotide analogs. Coupling yields with phosphoramidite (1) in solution or solid phase oligonucleotide analog synthesis are high and the 2-N-amidoethyl protecting group can be removed easily under standard conditions.
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Capaldi Daniel C.
Cheruvallath Zacharia S.
Cole Douglas L.
Ravikumar Vasulinga T.
ISIS Pharmaceuticals Inc.
Kunz Gary L.
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