Protecting agents from radiation hazards

Details Protecting agents from radiation hazards Protecting agents from radiation hazards

1994-12-16

1997-04-15

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 852, 424 854, 514 8, A61K 3818, A61K 3819, A61K 3820

Patent

active

056206852

ABSTRACT:
The present invention relates to pharmaceutical composition comprising SCF protein, IL-3 protein, GM-CSF protein and IL-6 protein. More specifically, the present invention relates to a protecting agent from radiation hazards, comprising SCF protein, IL-3 protein, GM-CSF protein and IL-6 protein.
The present invention also relates to a method for the treatment of patients with radiation hazards, which comprises administering the pharmaceutical composition according in a therapeutically effective amount to the patients.
The present invention has an excellent effect of enabling 100% survival of animals exposed to a lethal dose of radiations, which could not be attained by prior art pharmaceuticals.

REFERENCES:
Jones et al, Nature, 347, 13 Sep. 1990, pp. 188-189.
Neta et al. Journal of Immun., "Interdependence of the Radioprotective effects of Human Recombinant Interleukin" vol. 140, pp. 108-111, Jan. 1988 .

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