Protecting against canine oral papillomavirus (copy)

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4241921, 4241991, 4241841, 4241861, 435 5, 435 691, 435 693, 4352351, 4352402, 4353201, 536 2372, A61K 3912

Patent

active

058740899

ABSTRACT:
Recombinantly produced L1 major capsid proteins which mimic conformational naturalizing epitopes on human and animal papilloma virions including canine and equine papilloma virions are provided. These recombinant proteins are useful as vaccines for conferring protection against papillomavirus infection. Antibodies to the recombinant protein are also provided. Such antibodies are useful in the diagnosis and treatment of viral infection.

REFERENCES:
patent: 5437951 (1995-08-01), Lony et al.
Bell et al. A formation-inactivated vaccine protects against Mucosal Papillomavirus infection: A canine model, Pathobiology 62: 194-198 (1994).
Delius et al. Canine oral papillomavirus genomic sequence: A unique 1.5Kb interveiwing sequence between the Ez and Lz open reading frames. Virology 204, 447-452 (1994).

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