Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1996-10-01
1999-02-23
Mosher, Mary E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4241921, 4241991, 4241841, 4241861, 435 5, 435 691, 435 693, 4352351, 4352402, 4353201, 536 2372, A61K 3912
Patent
active
058740899
ABSTRACT:
Recombinantly produced L1 major capsid proteins which mimic conformational naturalizing epitopes on human and animal papilloma virions including canine and equine papilloma virions are provided. These recombinant proteins are useful as vaccines for conferring protection against papillomavirus infection. Antibodies to the recombinant protein are also provided. Such antibodies are useful in the diagnosis and treatment of viral infection.
REFERENCES:
patent: 5437951 (1995-08-01), Lony et al.
Bell et al. A formation-inactivated vaccine protects against Mucosal Papillomavirus infection: A canine model, Pathobiology 62: 194-198 (1994).
Delius et al. Canine oral papillomavirus genomic sequence: A unique 1.5Kb interveiwing sequence between the Ez and Lz open reading frames. Virology 204, 447-452 (1994).
Ghim Shin-je
Jenson A. Bennett
Schlegel C. Richard
Georgetown University School of Medicine
Mosher Mary E.
Salimi Ali R.
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