Protected diols for prostaglandin synthesis

Details Protected diols for prostaglandin synthesis Protected diols for prostaglandin synthesis

2007-01-09

2007-01-09

Witherspoon, Sikarl A. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C568S445000, C568S670000, C568S838000, C549S381000, C549S462000

Reexamination Certificate

active

11327876

ABSTRACT:
A process for the preparation of prostaglandin compounds having the formula (I):wherein A is selected from the group consisting of C1–C6alkyl groups; C7–C16aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6alkyl groups, halo and CF3; and (CH2)nOR′ wherein n is an integer from 1 to 3 and R′ represents a C6–C10aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6alkyl groups, halo and CF3; B is selected from OR″ and NHR″ wherein R″ is C1–C6alkyl groups; andrepresents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.

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