Proteasome inhibitors and methods of using the same

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Boron containing doai

Reexamination Certificate

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Reexamination Certificate

active

08058262

ABSTRACT:
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.

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