Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-02-16
2000-05-16
Patterson, Jr., Charles L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
435 691, 435 696, 530380, 530402, A61K 3800, A61K 3514, C12P 2106, C12P 2104
Patent
active
060637633
ABSTRACT:
The present invention relates to the single-chain thrombomodulin ("TM") and analogs thereof that are not susceptible to cleavage by proteases and retain the biological activity of thrombomodulin, as well as methods of use in, for example, antithrombotic therapy. Novel proteins, nucleic acid gene sequences, pharmaceuticals and methods of inhibiting thrombotic activity are disclosed.
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Andrews William H.
Clarke Jeffrey Homer
Light David Richard
Wydro Robert Michael
Young Patricia Ann
Patterson Jr. Charles L.
Schering Aktiengesellschaft
Stole Einar
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