Protease resistant modified interferon alpha polypeptides

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Reexamination Certificate

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C424S408000, C530S351000

Reexamination Certificate

active

07611700

ABSTRACT:
Processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided is a rational method for generating protein variants and the resulting variants.

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