Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...
Patent
1979-07-03
1981-05-05
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Stablizing an enzyme by forming a mixture, an adduct or a...
435172, 435222, 435836, C12N 996, C12N 956
Patent
active
042660319
ABSTRACT:
A novel protease product suitable for admixture to washing compositions and exhibiting substantially attenuated allergenic properties is prepared by cultivating strains of Bacillus licheniformis which have been mutated to block their synthesis of protease other than Subtilopeptidase A (subtilisin). The commercial Bacillus licheniformis derived protease products are mixtures of subtilisin and a non-serine protease of lower stability and greater allergenicity than subtilisin.
REFERENCES:
patent: 3748233 (1973-07-01), Viccaro
Keay, Fermentation Technology Today, Proc IV Int. Ferment Symp., Mar. 19-25, 1972, Kyoto, Japan, pp. 289-295.
Methods in Enzymology, vol. 19, pp. 199-215 (1970), article by Ottesen et al entitled The Subtilisins.
Aunstrup Knud
Gibson Keith
Nielsen Grethe C.
Schiff Hans
Tang Peter
Novo Industri A/S
Shapiro Lionel M.
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