Protease K resistant arginine deiminase, its method of preparati

Details Protease K resistant arginine deiminase, its method of preparati Protease K resistant arginine deiminase, its method of preparati

1994-02-18

1994-12-13

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435815, 530416, C12N 978, C07K 1504

Patent

active

053729420

ABSTRACT:
A highly purified arginine deiminase is obtained using a two-step purification procedure. The arginine deiminase is isolated and purified from various species of mycoplasmas and is resistant to proteinase K. The growth of tumor cells can be inhibited by administering proteinase K-resistant arginine deiminase or a PEG-conjugate thereof.

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