Protease inhibition for prevention or treatment of heart...

Details Protease inhibition for prevention or treatment of heart... Protease inhibition for prevention or treatment of heart...

2011-01-04

2011-01-04

Saeed, Kamal A (Department: 1626)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Reexamination Certificate

active

07862811

ABSTRACT:
Methods, and compositions to prevent and/or treat acute or chronic right ventricular failure from pressure over load (RVPO). In one embodiment, the method includes the inhibition of at least one cysteine protease. In other embodiments, the method includes the inhibition of MMP activity to prevent or treat right ventricular failure from acute pressure over load (RVPO). In another embodiment, combination therapies are included to inhibit cysteine protease activity and MMP activity.

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