Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1989-06-14
1991-03-19
Jones, W. Gary
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
210206, 2102572, 210259, 210263, 210295, 21032172, 2105021, 210639, 210690, 502401, 502404, 604 5, 604406, 424529, 436178, B01D 3602
Patent
active
050008544
ABSTRACT:
An arrangement for collecting blood from a source of blood employs a filter chamber having a substantially predefined volume for accumulating the collected blood, and first and second access ports for receiving the collected blood and for venting the filter chamber, respectively. A protamine filter is arranged within the filter chamber, and preferably is formed of regenerated cellulose hollow fibers which have been activated with CNBr and have protamine immobilized thereon. The amount of protamine immobilized thereon is controlled in a variety of ways, prior to installation and sealing of the filter element within the filter chamber. In a practical embodiment, the first port of the filter chamber is coupled to a conventional cannula needle for communicating transdermally with a living being or through a membrane of a blood storage container. The second port is coupled to a conventional syringe which applies a suction for facilitating withdrawal of the blood. In other embodiments, the protamine is immobilized on a biocompatible polymer substrate by covalent bonding.
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Jones W. Gary
The University of Michigan
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