Prosthetic RNA and use thereof to modify RNA expression

Details Prosthetic RNA and use thereof to modify RNA expression Prosthetic RNA and use thereof to modify RNA expression

1995-06-06

1998-03-10

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

435 691, 4351723, 536 231, 536 241, 536 245, C12N 500, C12N 502, C12N 1500, C07H 2102

Patent

active

057260591

ABSTRACT:
Translation characteristics of an mRNA molecule in a cell can be altered by providing a prosthetic RNA molecule that includes a regulatory sequence element and a sequence element complementary to a portion of the mRNA molecule. Alteration can affect the translation rate, the mRNA stability, or the localization of the mRNA molecule.

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