Prosthetic ligaments

Details Prosthetic ligaments Prosthetic ligaments

1992-04-22

1993-11-23

Isabella, David

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Hair or skin

623 66, A61F 208

Patent

active

052639843

ABSTRACT:
Disclosed is a prosthetic ligament comprising a Plurality of substantially aligned, elongated filaments. Each filament is a dry, porous, volume matrix of biocompatible and bioresorbable fibrils, at least some of which are crosslinked. The fibrils are short segments of longer fibers of polymeric connective tissue components, or analogs thereof. Each filament establishes a bioresorbable scaffold adapted for ingrowth of ligament fibroblasts, the scaffold and the ingrown fibroblasts supporting natural ligament tensile forces. Also disclosed are methods of fabricating the prosthetic ligament, and methods of regenerating ligamentous tissue in vivo.

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