Prosthesis with in-wall modulation

Details Prosthesis with in-wall modulation Prosthesis with in-wall modulation

1996-12-03

1998-10-20

Brittingham, Debra S.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Stent structure

623 11, 623 12, A61F 206, A61F 204

Patent

active

058240500

ABSTRACT:
The wall of a prosthesis has a region which modulates communication through the porosity of the wall. The prosthesis is unitary, but may be assembled in successive bodies which are coalesced, so that the porous microstructure changes distinctly at stages through the thickness dimension of the wall. One embodiment is formed entirely of fluoropolymer, and has at least one surface adapted to support tissue regeneration and ingrowth. The modulation region is a stratum of high water entry pressure that reduces pulsatile hydraulic pressure transmission, or locally alters fluid-born-distribution of biological material through the wall and allows more natural gradients for tissue regeneration and growth in the outer region of the wall.

REFERENCES:
patent: 4629458 (1986-12-01), Pinchuk
patent: 4955899 (1990-09-01), Della Corna et al.
patent: 5028597 (1991-07-01), Kodama et al.
patent: 5061276 (1991-10-01), Tu et al.
patent: 5123917 (1992-06-01), Lee
patent: 5152782 (1992-10-01), Kowligi et al.
patent: 5163951 (1992-11-01), Pinchuk et al.
patent: 5229045 (1993-07-01), Soldani
patent: 5354329 (1994-10-01), Whalen
patent: 5413597 (1995-05-01), Krajicek
patent: 5453278 (1995-09-01), Chan et al.

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