Prosthesis with improved biocompatibility made with N-vinyl poly

Details Prosthesis with improved biocompatibility made with N-vinyl poly Prosthesis with improved biocompatibility made with N-vinyl poly

1996-10-16

1998-02-03

Prebilic, Paul B.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

623 8, 623 4, 623 15, 523113, 523115, A61F 202

Patent

active

057139601

ABSTRACT:
An injectable or implantable material for soft tissue augmentation comprising a hydrogel containing both hydrophobic and hydrophilic domains is prepared by copolymerizing a hydrophilic monomer, such as water soluble N-vinylpyrrolidone with non-water soluble monomers, such as N-vinyl carbazole, its derivatives, or a non-water soluble derivative of N-vinylpyrrolidone. Also suitable for injection into direct contact with body tissue are hydrogels prepared by cross-linking polyvinylpyrrolidone. The hydrogel may be either solid or composed of particles. The hydrogel may also be enclosed within a flexible porous or nonporous envelope.

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