Prosthesis with improved biocompatibility

Details Prosthesis with improved biocompatibility Prosthesis with improved biocompatibility

1990-07-06

1992-05-26

Isabella, David

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

623 8, A61F 202

Patent

active

051163713

ABSTRACT:
An implantable prosthesis comprises a hydrogel enclosed within a flexible envelope. The hydrogel contains both hydrophilic and hydrophobic domains. It is prepared by copolymerizing a hydrophilic monomer such as water soluble N-vinylpyrrolidone, acrylates or methacrylates with non-water soluble monomers such as acrylates, methacrylates, N-vinyl carbazole, its derivatives, or a non-water soluble derivative of N-vinylpyrrolidone. The flexible envelope may be either porous or non-porous. The hydrogel may be either solid or composed of particles of a size greater than the porosity of the envelope.

REFERENCES:
patent: 3293663 (1966-12-01), Cronin
patent: 4138382 (1979-02-01), Polmanteer
patent: 4157085 (1979-06-01), Austad
patent: 4517326 (1985-05-01), Cordts et al.
patent: 4648880 (1987-03-01), Brauman
patent: 4731081 (1988-03-01), Tiffany
patent: 4790848 (1988-12-01), Cronin
K. Kliment, et al; Use of Spongy Hydron in Plastic Surgery; 1968 J. Biomed. Mater. Res. vol. 2, pp. 237-243.
J. S. Calnan, et al; Clinical and Experimental Studies of Polyhydroxyehtylmethacrylate Gel ("Hydron") for Reconstructive Surgery; British J. Plastic Surg. vol. 24, pp. 113-124.

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