Prosthesis and method for making the same

Bleaching and dyeing; fluid treatment and chemical modification – Treatment of hides – skins – feathers and animal tissues – Internal tissues

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3 1, 8 9419R, 8 9433, 128 1R, A61F 124

Patent

active

040825078

ABSTRACT:
A method is provided for controlling thrombogenicity of a vascular graft prosthesis by controlling the surface charge of at least the intimal surface of the prosthesis by reaction with a compound selected from the group consisting of albumin, glyoxals, ethoxyformic anhydride, formic acid, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and the like. The surface charge is then stabilized by treatment with glutaraldehyde, dialdehyde starch, formalin or the like.

REFERENCES:
patent: 2900644 (1959-08-01), Rosenberg
patent: 3927422 (1975-12-01), Sawyer
patent: 3966401 (1976-06-01), Hancock et al.
patent: 3988728 (1976-11-01), Dardik

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