Prostatic stem cells, isolation and uses

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

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Reexamination Certificate

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08067230

ABSTRACT:
Prostatic stem cells have been isolated. Benign prostatic hyperplasia and other proliferative diseases of the prostate may arise in prostatic stem cells. The prostatic stem cells are used as a research tool for studying cancer and other proliferative diseases of the prostate, and for developing diagnostics and therapeutics for proliferative diseases of the prostate. Antibodies to the antigens expressed by prostatic stem cells can be used as therapeutics or diagnostics or can be used to deliver therapeutic or diagnostic agents directly to the prostatic stem cells.

REFERENCES:
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patent: 6984522 (2006-01-01), Clarke et al.
Collins et al. J. of Cell Sci, 114: 3865-3872, 2001.
Goto et al. Abstract #394, Journal of Urology, (Apr. 2004) vol. 171, No. 4, Supplement, pp. 104. print. Meeting Info.: Annual Meeting of the American Urological Association. San Francisco, CA, USA. May 8-13, 2004.

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