Prostate-specific membrane antigen and uses thereof

Details Prostate-specific membrane antigen and uses thereof Prostate-specific membrane antigen and uses thereof

2003-07-02

2008-07-15

Kemmerer, Elizabeth C. (Department: 1649)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

X-ray contrast imaging agent

Reexamination Certificate

active

07399461

ABSTRACT:
This invention provides a method of administering methotrexate triglutamate (MTXglu3), an inhibitor of the neurocarboxypeptidase activity of prostate specific membrane antigen, to a subject so as to inhibit release of glutamate by N-acetylaspartylglutamic acid (NAAG) hydrolysis in the subject.

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