Prostate specific antigen (PSA)-proteinase inhibitor complexes

Details Prostate specific antigen (PSA)-proteinase inhibitor complexes Prostate specific antigen (PSA)-proteinase inhibitor complexes

1995-06-07

1999-06-15

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435219, 530350, C12N 964

Patent

active

059121580

ABSTRACT:
Prostate specific antigen (PSA) is a protein that can form complexes with proteinase inhibitors such as .alpha..sub.1 -antichymotrypsin. The invention is characterized in that the measurement of the ratio of free PSA to PSA bound to proteinase inhibitors (free PSA:PSA-proteinase inhibitor complex) is useful in the diagnosis of patients with prostate cancer.

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