Prostanoids and synthesis thereof

Details Prostanoids and synthesis thereof Prostanoids and synthesis thereof

1987-04-30

1989-08-08

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D26120

Patent

active

048554375

ABSTRACT:
Prostaglandin analogues which include a bicyclic isoxazolidine nucleus are disclosed. These analogues may be used to prepare other prostaglandins. Essential to the synthesis is intramolecular nitrone-alkene cycloaddition involving an alkenyl nitrone in which the reacting centers are separated by two carbons.

REFERENCES:
patent: 4112224 (1978-09-01), Bundy
patent: 4275213 (1981-06-01), Bundy

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