Prostanoid compounds and pharmaceutical compositions

Details Prostanoid compounds and pharmaceutical compositions Prostanoid compounds and pharmaceutical compositions

1982-11-10

1983-10-11

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544396, 544399, 424 45, 544400, 546187, 424246, 546188, 546190, 4242485, 546208, 546216, 42424853, 546217, 546230, 42424855, 546232, 546233, 424250, 546234, 546235, 424267, 546238, 546239, 424274, 542426, 560 10, 424304, 560 16, 560 36, 424309, 560 43, 560121, 424305, 562426, 562441, 424319, 562444, 562448, 544 581, 562452, 562455, 544 582, 562456, 562457, 544 585, 562433, 562503, 544 586, 2602433, 2602444, 544 587, 2602457, 260239BF, 544 82, 2603306, 260465D, 544 85, 548523, 548566, 544 86, 548567, 548573,

Patent

active

044092130

ABSTRACT:
Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH-- or --(CH.sub.2).sub.2 --; R is alkyl having a terminal --COOH or ester group; and Y is amino or substituted amino, particularly heterocyclic amino.
The compounds have bronchodilator activity and/or inhibit blood platelet aggregation.
The preparation and pharmaceutical formulation of the compounds is also described.

REFERENCES:
patent: 4182903 (1980-01-01), Favara et al.
patent: 4189606 (1980-02-01), Favara et al.
patent: 4239778 (1980-12-01), Venton et al.
LeBreton et al, Proc. Natl. Acad. Sci., USA, vol. 76 (1979) pp. 4097-4101.

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