Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-07-10
1981-05-05
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424246, 42424853, 42424855, 424250, 424267, 424274, 544 581, 544 582, 544171, 544396, 544399, 542426, 526238, 546239, 260239BF, 2603264, 260333, A61K 3155, A61K 31535, C07D29514
Patent
active
042658918
ABSTRACT:
Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH-- or --(CH.sub.2).sub.2 --; R is alkyl having a terminal --COOH or ester grup; and Y is amino or substituted amino, particularly heterocyclic amino.
The compounds have bronchodilator activity and/or inhibit blood platelet aggregation.
The preparation and pharmaceutical formulation of the compounds is also described.
REFERENCES:
Lepetit, Abstract of German Patent 2,705,797, 9-1-77.
Enke et al., Abstract Papers of ACS, 176th Meeting, MEDI, 28 (1978).
Orth et al., Topics in Current Chemistry, 72, 51-97 (1977).
Collington Eric W.
Finch Harry
Newton Roger F.
Wallis Christopher J.
Glaxo Group Limited
Jiles Henry R.
Ramsuer R. W.
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