Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-11-19
1999-08-03
Killos, Paul J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546339, 560 11, 560 27, 558 61, 568 28, 568 67, 564162, 514252, A01N 4358
Patent
active
059325860
ABSTRACT:
This invention relates to ortho substituted phenyl compounds as inhibitors of prostaglandin synthase, to pharmaceutical compositions comprising such compounds and to methods of using such compounds as antiinflammatory and antipyretic agents. The class of compounds useful in this method of treatment is represented by Formula I below: ##STR1##
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Newkome et al J. Org. Chem 1980, 45:4380.
Bushby et al J. Chem Soc. Perkin Trans I 1986 721.
Hori et al Chem. Pharm. Bull 1974 22:2020.
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Batt Douglas Guy
Orwat Michael James
Petraitis Joseph James
Pinto Donald Joseph Phillip
Pitts William John
DuPont Pharmaceuticals Company
Killos Paul J.
Kondrad Karen H.
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