Prostaglandin E receptors, their DNA and production

Details Prostaglandin E receptors, their DNA and production Prostaglandin E receptors, their DNA and production

1996-07-22

1998-09-08

Teng, Sally P.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 235, 4352523, 43525411, 4353201, 435325, C12N 1512, C07K 14705

Patent

active

058044159

ABSTRACT:
Disclosed are (1) a protein capable of receiving PGE, (2) a recombinant DNA coding for said protein, (3) a vector having said DNA, (4) a transformant carrying said vector, and (5) a method for producing said protein wherein said transformant is cultured in a culture medium, the protein being useful not only in cloning other PGE receptor genes, clarifying the structure of PGE receptors and elucidating the function of PGE, but also in searching for PGE antagonists and agonists and so on.

REFERENCES:
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Yukihiko Sugimoto et al., Cloning and Expression of a cDNA for Mouse Prostaglandin E Receptor EP.sub.3 Subtype, The Journal of Biological Chemistry, vol. 267, No. 10, pp. 6463-6466 (Apr. 5, 1992).
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