Prostaglandin derivatives

Harness for working animal

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

542426, 542429, 542430, 542441, 2603436, C07D30720, C07D40712

Patent

active

042347203

ABSTRACT:
Prostaglandin type compounds of the formula ##STR1## where X is CH.sub.2 --CH.sub.2, CH.dbd.CH cis or C.tbd.C; Y is CH.sub.2 or O; Z is H, OH, CH.sub.3 or CH.sub.2 OH and R is a linear, branched or cyclo alkyl chain of 3 to 7 carbon atoms, can be prepared by essentially a one-step reaction from a new intermediate of the formula ##STR2## where R represents a linear, branched or cyclo alkyl group of 3 to 7 carbon atoms; P is a removable protective group and z is H, OP,CH.sub.3 or CH.sub.2 OP.
The intermediate is useful in making known and new PGEs useful as antihypertensives, gastric acid secretion inhibitors and smooth muscle stimulants.

REFERENCES:
Corey et al., J.A.C.S. 95 (1973) pp. 6832-6833.
Corey et al., J.A.C.S. 94 (1972) pp. 7210-7211.
Corey et al., J.A.C.S. 90 (1968) pp. 5615-5616.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Prostaglandin derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prostaglandin derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prostaglandin derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-599275

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.