Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1996-08-22
1997-12-16
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
424450, 554228, 560121, C07C40500, H01K 31557
Patent
active
056985908
ABSTRACT:
Prostaglandin E.sub.1 ester derivatives of the formula (I): ##STR1## wherein the R' groups are the same as each other and are C4-12 alkyl; or cyclodextrin clathrates thereof, liposome formulations containing them, and pharmaceutical compositions containing them, as active ingredient.
The compounds of formula (I) have the effect of increasing blood flow and are useful for the prevention and/or treatment of peripheral circulatory disorder, decubitus, or skin ulcers, or for the maintenance of blood flow.
Hamano Shin-ichi
Matsumoto Ryoji
Nishiura Akio
Seko Takuya
Gerstl Robert
Ono Pharmaceutical Co. Ltd.
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