Prostaglandin analogues

Details Prostaglandin analogues Prostaglandin analogues

1984-05-04

1986-03-18

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514573, 514690, 549465, 560119, 560121, 562501, 562503, 568374, 568379, C07C17700, A61K 31557

Patent

active

045769621

ABSTRACT:
The 13,14-didehydro-15-oxo analogues of natural prostaglandins possess high cytoprotective activity and low diarrheogenic activity, low anti-hemostatic activity and low smooth muscle contraction activity.

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F. F. Sun et al., "Advances in Prostaglandin and Thromboxane Research," vol. 1, p. 163 (1976), Samuelson & Bouletti, Ed., Raven Press, NY.
Gandolfi et al., "Advances in Prostaglandin and Thromboxane Research," vol. 1, p. 209 (1976), Samuelson & Bouletti, Ed., Raven Press, NY.
Epolitti et al., Gastroenterology, 80, pp. 55-59 (1981).

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