Prostacyclin treatment of thrombosis

Details Prostacyclin treatment of thrombosis Prostacyclin treatment of thrombosis

1981-07-02

1983-09-13

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424253, 424258, 424263, 424285, A61K 31505, A61K 3152, A61K 3144, A61K 3134

Patent

active

044042124

ABSTRACT:
Pharmaceutical combinations comprising (a) prostacyclin, dihydroprostacyclin or a pharmaceutically acceptable salt of either of these, and (b) a phosphodiesterase inhibitor. Pharmaceutical formulations comprising a combination as above and a pharmaceutically acceptable carrier. Methods are disclosed for preparing the combinations and the formulations.
The combinations and formulations are useful for preventing or minimizing platelet aggregation in blood, blood products or blood substitutes for example in the treatment of thrombosis, gastric lesions and wounds, and in the extra-corporeal circulation of blood and in blood separation processes.

REFERENCES:
patent: 3954787 (1976-05-01), Monkhouse
patent: 3962243 (1976-06-01), Roldan et al.
patent: 3998953 (1976-12-01), Konz et al.
patent: 4009282 (1977-02-01), Voorhees
patent: 4051236 (1977-09-01), Harris et al.
patent: 4158667 (1979-06-01), Axen
Prostaglandins, 13(3), 377-388 (1977)-Gorman et al.
Prostaglandins, 14(1), 39-50 (1977)-Gerrard et al.
Brit. J. Pharm. 59(3), 438-439 (1977)-Bonta et al.
Prostaglandins, 13(3) 389-397 (1977)-Tateson et al.
Nature 267, pp. 850-852 (1977)-Best et al.
Biochem. J. 121 185-196 (1971)-Mills et al.
Pharmacol. of Platelet Aggre. Inhibit-Thomb. Diath. Haemorrh-Supp. 42, 175-184 (1970)-Mills et al.
Biochem. Biophy. Res. Comm. 76(3) 828-835 (1977) Lapetina et al.
Biochem. J., 120, 709-718 (1970)-Ball et al.

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