Prosaposin as a neurotrophic factor

Details Prosaposin as a neurotrophic factor Prosaposin as a neurotrophic factor

1993-07-30

1996-11-05

Allen, Marianne P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530350, 530399, 514 2, 514 8, 514 13, 4352402, A61K 3817, A61K 3818, C12N 1500

Patent

active

055717870

ABSTRACT:
Prosaposin, saposin C and various peptide fragments of saposin C stimulate neurite outgrowth in vitro. In addition, prosaposin and saposin C promote increased myelination ex vivo. Prosaposin is present in large neurons of the brain, including both upper and lower motor neurons.

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