Prorenin antibody and renin-active substance containing the same

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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5303879, 435 71, C07K 1600, G01N 3353

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active

059455128

ABSTRACT:
Provided by the present invention are a human prorenin profragment N-terminated peptide antibody capable of specifically recognizing a peptide containing at least 15 amino acid residues from the first leucine residue to the 15th arginine residue in the N-terminated peptide of the human prorenin profragment and a complex of the same with human prorenin. The antibody can be used as a prorenin assay reagent. The human prorenin profragment N-terminated peptide antibody is useful as a reagent for the assay of human prorenin in blood.

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R. Day et al., J. Hypertension, 4(3), 375-381 (1986).
M. Price-Jones et al., Clin. and Exper. Hypertension, 15(4), 619-640 (1993) .

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