Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-10-30
2007-10-30
Dentz, Bernard (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S341000, C514S385000, C514S394000, C514S338000, C514S333000, C514S489000, C514S367000, C514S343000, C546S272700, C546S273400, C546S278400, C546S275400, C546S275100, C546S261000, C544S132000, C562S032000
Reexamination Certificate
active
10492059
ABSTRACT:
The present invention includes ketone derivatives (I) and (II), which are useful as cathepsin K inhibitors. The described invention also includes methods of making such ketone derivatives as well as methods of using the same in the treatment of disorders, including osteoporosis
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patent: 98/16505 (1998-04-01), None
Groarke, et. al. “Synthesis of ketomethylene amino pseudopeptide analogues via reductive amination of glyoxals derived from alpha-amino acids”, Bioorganic & Medicinal Chemistry Letters, vol. 10, No. 2, Junary 2000.
“Design and Synthesis of Novel [60]Fullerene Derivatives as Poetential HIV Aspartic Protease Inhibitors”, Marcorin et. al., Organic Letters, 200, vol. 2, No. 25, 3955-3958.
Groakre, M. et al., “Synthesis fo ketomethylene amino pseudopeptide analogues via reductive amination of glyoxals derived from alpha-amino acids,”Bioorganic&Medicinal Chemistry Letters, vol. 10, No. 2, Jan. 2000, pp. 153-155.
Catalano John George
Deaton David Norman
Coulter Kathryn L.
Dentz Bernard
Lemanowicz John L.
Robinson Binta
SmithKline Beecham Corporation
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