Propofol composition comprising pentetate

Details Propofol composition comprising pentetate Propofol composition comprising pentetate

1998-10-22

2000-02-22

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514731, A61K 3105

Patent

active

060281081

ABSTRACT:
A sterile pharmaceutical composition for parenteral administration comprising an oil-in-water emulsion of propofol and an amount of pentetate sufficient to prevent significant growth of microorganisms for at least 24 hours after adventitious extrinsic contamination.

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patent: 5614170 (1997-03-01), Cacheris et al.
patent: 5714520 (1998-02-01), Jones et al.
Muller et al., Pharm. Ind. 55(10), 1993, 948-950.
Holzgraefe, M. et al., Clin. Tox 24(3), 1986, 235-244.
Inactive Ingredients Guide, FDA, 1996, 101 (Doc.#139955).
J. Dairy Science, 68, Suppl. 1, 1985, 210.

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