Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-12-22
1990-03-27
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514320, 514408, 514428, 514906, A61K 31445, A61K 3140
Patent
active
049121162
ABSTRACT:
A method for the treatment of pollakiurea in a subject in need thereof, comprising the step of administering to said subject an effective antipollakiurea amount of a propiophenone of the formula (I) ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each independently represents hydrogen, halogen, lower alkyl- or halogeno-lower-alkyl, lower-alkoxy, or cycloalkyl having 3-8 carbon atoms, two of which R.sub.1, R.sub.2, and R.sub.3 groups may combine to form methylenedioxy or ethyleneoxy, R.sub.4 represents hydrogen or a lower-alkyl, and A represents pyrrolidinyl-, piperidinyl-, morpholinyl-, or azepinyl or a pharmaceutically-acceptable acid addition salt thereof, is disclosed.
REFERENCES:
patent: 4638009 (1987-01-01), Itho et al.
Pietra et al., Chem. Abst. 105(11):91189u, (1986).
The Merck Index, 10th Ed., (1983), pp. 520, 1363, Reference Nos. 3555 and 9351.
Krupp, Marcus A., Medical Diagnosis and Treatment, (1976), p. 521.
Physicians' Desk Reference, 38th, (1984), p. 1900, Urispas.
Itoh Yasuo
Kato Hideo
Koshinaka Eiichi
Morikawa Kouji
Yamauchi Toshie
Hokuriku Pharmaceutical Co., Ltd.
Hueschen Gordon W.
Robinson Douglas W.
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