Propiophenone derivative and a process for preparing the same

Details Propiophenone derivative and a process for preparing the same Propiophenone derivative and a process for preparing the same

1995-04-27

1998-11-03

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 41, 536 181, A61K 3170, C07M 1500

Patent

active

058308733

ABSTRACT:
##STR1## wherein X is O, S or methylene, OY is a protected or unprotected OH, Z is .beta.-D-glucopyranosyl or 4-O-(.alpha.-D-glucopyranosyl)-.beta.-D-glucopyranosyl or wherein one or more hydroxy groups of these groups may optionally be acylated, and the dotted line means the presence or absence of a double bond, or a pharmaceutically acceptable salt thereof. Said compounds have excellent hypoglycemic activity so that they are useful in the prophylaxis or treatment of diabetes.

REFERENCES:
patent: 3984394 (1976-10-01), Westall et al.
patent: 4031260 (1977-06-01), Westall et al.
patent: 4049715 (1977-09-01), Bell
patent: 4665058 (1987-05-01), Diedrich et al.
patent: 4684627 (1987-08-01), LeVeen et al.
patent: 4760135 (1988-07-01), Diedrich et al.
patent: 4840939 (1989-06-01), LeVeen et al.
patent: 5110801 (1992-05-01), Leveen et al.
patent: 5424406 (1995-06-01), Tsujihara et al.
Diedrich, Biochim. Biophys. Acta, 71, 688 (1963).
Rossetti et al., Diabetes Care, 13, 610 (1990).
Rossetti et al., J. Clin. Invest., 79, 1510 (1987).
Rossetti et al., J. Clin. Invest., 80, 1037 (1987).
Kahn et al., J. Clin. Invest., 87, 561 (1991).
Unger et al., Diabetologia, 28, 119 (1985).
Oldendorf et al., Stroke, 14, 388 (1983).
Winget et al., Biochemistry, 8, 2067 (1967).
Vick et al., Amer. J. Physiol., 224, 552 (1973).
Diedrich, Arch. Biochem. Biophys., 117, 248 (1966).
Evans et al., Arch. Biochem. Biophys., 199, 342 (1980).
Bode et al., Biochim. Biophys. Acta, 290, 134 (1972).
Okada et al., Abstract of J. Nutr. Sci. Vitaminol.
T. Fujiwara et al., Diabetes, 37, 1549 (1988).
Szabo et al., Acta Aliment, 11, 31-37 (1982).

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