Prophylaxis and treatment of thromboembolic disorders in man and

Details Prophylaxis and treatment of thromboembolic disorders in man and Prophylaxis and treatment of thromboembolic disorders in man and

1981-06-16

1984-05-29

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424 19, 424 31, A61K 3300

Patent

active

044514549

ABSTRACT:
Sodium bicarbonate and potassium bicarbonate are systemic anticoagulants that when administered internally inhibit blood coagulation in man and in warm-blooded animals. As such, they are useful and effective in the treatment and/or prevention of thromboembolic diseases, myocardial infarction or other conditions associated with high risk of thromboembolism. Sodium bicarbonate is especially useful for preventing clotting of ptient's blood during kidney dialysis and for preserving citrated human or animal whole blood and plasma indefinitely under proper storage conditions.

REFERENCES:
patent: 3857949 (1974-12-01), Garzia
Wong, D. et al., JAMA, 244(1), 61-62 (1980).
Wong, D., J. Pharm. Sci., 69(8), 978-980 (Aug. 1980).

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